Mykel Williams
NFL Injury Report

Mykel Williams Injury Status

San Francisco 49ers • DE
Latest Injury Status
active
A

Williams started Week 7 prep as a non-participant but gradually worked his way up to full participation in Friday's session. The defensive end has overcome his knee injury in time to suit up opposite Keion White for Sunday's game.

Injury Details

Body Part
—
Location
—
Side
—
Expected Return
Not announced

Betting Research

Player availability can affect minutes, usage, matchup assignments, team totals and player-prop markets. Compare the latest injury information with current prices before making a betting decision.

View Mykel Williams Props NFL Injury Reports NFL Player Props NFL Parlay Calculator Upcoming Games Compare Odds Expert Picks

Mykel Williams Injury History

November 2, 2026
active
Williams (knee) does not have any injury designation ahead of Sunday's game against the Falcons.
October 24, 2026
active
October 23, 2026
questionable • Knee
Not Specified
Williams (knee) was estimated to be a nonparticipant in Wednesday's walkthrough practice, Harrison Rich of the San Francisco Chronicle reports.
October 22, 2026
questionable • Knee
Not Specified
questionable
October 22, 2026
active
Williams (knee) is active for Monday night's game against the Commanders, Brooke Evans of the team's official site reports.
October 19, 2026
active
October 19, 2026
questionable • Knee
Not Specified
Williams (knee) is questionable for Monday night's game against the Commanders.
October 18, 2026
questionable • Knee
Not Specified
questionable
October 15, 2026
active
The 49ers activated Williams (knee) from the reserve/PUP list Saturday, and he no longer carries an injury designation into Sunday's NFC West tilt against the Seahawks.
October 11, 2026
active • Knee - ACL
Surgery
Williams (knee) is listed as questionable ahead of Sunday's game against the Seahawks.
October 6, 2026
out • Knee - ACL
Surgery
The 49ers opened Williams' (knee) 21-day practice window Wednesday to return from the reserve/PUP list, Matt Maiocco of NBC Sports Bay Area reports.
September 10, 2026
out • Knee - ACL
Surgery
out
September 8, 2026
out • Knee - ACL
Surgery
Williams (knee) was moved to the reserve/PUP list by the 49ers on Sunday.
August 22, 2026
out • Knee - ACL
Surgery
Coach Kyle Shanahan said Tuesday that Williams (knee) is considered a "long shot" to play in Week 1 against the Rams, Dylan Grausz of NBC Sports reports.

Latest Mykel Williams Injury Updates

This page tracks available injury information for Mykel Williams, including reported status, injury details, expected return information and updates that may be relevant when evaluating NFL betting markets.

Injury designations can change close to game time. Check the latest market prices and confirmed player availability before placing a wager.